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视网膜母细胞瘤患者的白内障手术及人工晶状体植入术

Cataract surgery and intraocular lens implantation in patients with retinoblastoma.

作者信息

Portellos M, Buckley E G

机构信息

Duke University Eye Center, Durham, NC 27710, USA.

出版信息

Arch Ophthalmol. 1998 Apr;116(4):449-52. doi: 10.1001/archopht.116.4.449.

Abstract

OBJECTIVE

To report the visual outcome and complications after extracapsular cataract extraction with posterior chamber intraocular lens (IOL) implantation in eyes that underwent external beam radiotherapy for the treatment of retinoblastoma.

METHODS

Eleven eyes of 8 patients aged 1.5 to 8.0 years at the time of surgery for irradiation-induced cataract were observed for 6 to 39 months (mean [+/-SD], 20+/-10 months). A standard technique of extracapsular cataract extraction, posterior chamber IOL implantation, pars plana posterior capsulotomy, and pars plana anterior vitrectomy was performed in 9 eyes, and secondary IOL placement was performed in 2 eyes.

RESULTS

All eyes that underwent primary IOL implantation achieved visual acuities equal to or better than those best ever recorded prior to the development of the cataract. There were no postoperative complications, and all eyes experienced minimal postoperative inflammation. The 2 eyes that underwent secondary IOL implantation achieved their best-corrected aphakic visual acuities but experienced a prolonged course of postoperative inflammation.

CONCLUSION

Intraocular lens placement in the posterior chamber of eyes with regressed retinoblastoma and irradiation-induced cataract seems to be a safe and effective method for the correction of aphakia.

摘要

目的

报告接受视网膜母细胞瘤外照射放疗的眼睛在行囊外白内障摘除联合后房型人工晶状体(IOL)植入术后的视力结果及并发症。

方法

对8例手术时年龄为1.5至8.0岁的因放疗诱发白内障而接受手术的患者的11只眼睛进行了6至39个月(平均[±标准差],20±10个月)的观察。9只眼睛采用了标准的囊外白内障摘除、后房型IOL植入、平坦部后囊切开术和平坦部前段玻璃体切除术技术,2只眼睛进行了二期IOL植入。

结果

所有接受一期IOL植入的眼睛术后视力均达到或优于白内障发生前记录的最佳视力。术后无并发症,所有眼睛术后炎症均很轻微。2只接受二期IOL植入的眼睛达到了最佳矫正无晶状体视力,但术后炎症持续时间较长。

结论

在视网膜母细胞瘤消退且有放疗诱发白内障的眼睛后房植入人工晶状体似乎是矫正无晶状体的一种安全有效的方法。

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