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Middle cerebral artery main stem thrombosis in two siblings with familial thrombotic thrombocytopenic purpura.

作者信息

Kelly P J, McDonald C T, Neill G O, Thomas C, Niles J, Rordorf G

机构信息

Department of Neurology, Massachusetts General Hospital, Boston 02114, USA.

出版信息

Neurology. 1998 Apr;50(4):1157-60. doi: 10.1212/wnl.50.4.1157.

DOI:10.1212/wnl.50.4.1157
PMID:9566416
Abstract

Idiopathic thrombotic thrombocytopenic purpura (TTP) is frequently complicated by microinfarcts in cerebral cortex and subcortical white matter. We describe two sisters who suffered massive hemispheric infarction due to thrombosis of the middle cerebral artery main stem during exacerbations of TTP. Acute TTP may be associated with intraluminal thrombosis of large-diameter arteries in addition to arterioles and capillaries.

摘要

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Thrombotic thrombocytopenic purpura with concomitant small- and large-vessel thrombosis, atypical posterior reversible encephalopathy syndrome and cerebral microbleeds.
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