治疗性流产后外周激素水平的变化。

Changes in peripheral hormone levels after therapeutic abortion.

作者信息

Saunders D M, Kelso I M, Grudzinskas J G, Hughes G J, Wilson G R

出版信息

Eur J Obstet Gynecol Reprod Biol. 1978 Feb;8(1):1-4. doi: 10.1016/0028-2243(78)90002-3.

Abstract

Plasma levels of progesterone, 17 alpha-OH progesterone, hPL and beta-subunit hCG were measured in a group of women for 24 h after therapeutic abortion. Progesterone, hCG and hPL levels fell more rapidly than 17 alpha-OH progesterone levels. This might suggest that the main site of synthesis of 17 alpha-OH progesterone is probably in the corpus luteum of pregnancy or that the prolonged half-life of hCG maintains the corpus luteum to secrete longer. Human placental lactogen fell dramatically within 4 h but the hCG level was maintained. This difference probably reflects only the differences in half-lives of these hormones.

摘要

对一组妇女在治疗性流产后24小时内测定其血浆中孕酮、17α-羟孕酮、人胎盘催乳素（hPL）和人绒毛膜促性腺激素β亚基（β-hCG）的水平。孕酮、hCG和hPL水平下降速度比17α-羟孕酮水平更快。这可能表明17α-羟孕酮的主要合成部位可能是妊娠黄体，或者是hCG较长的半衰期维持黄体分泌的时间更长。人胎盘催乳素在4小时内急剧下降，但hCG水平保持稳定。这种差异可能仅反映了这些激素半衰期的不同。