Bogatyreva N E, Shevchenko E V, Iakovenko E V, Chernysh A M, Raĭnov M V, Antonov V F
Sechenov Moscow Medical Academy, Moscow, Russia.
Biofizika. 1998 Jan-Feb;43(1):57-60.
The lifetime of lipid bilayer membranes formed from hydrogenated egg lecithin has been studied at the phase transition from liquid crystalline state to the gel. It was shown the lowering of the membrane stability at the phase transition temperature of hydrogenated egg lecithin. Using lifetime values and measured surface tension of bilayer the critical radius of transmembrane pore has been evaluated in comparison with experimental data, obtained by transmembrane current fluctuation registration. It was shown that lifetimes of bilayer lipid membrane in gel state conform data, derived from Deryagin-Gutop-Prokhorov's theory. The radii of pores corresponded to maximal transmembrane current fluctuations are close to critical values of pores in the gel state.
氢化卵磷脂形成的脂质双分子层膜在从液晶态到凝胶态的相变过程中的寿命已经得到研究。结果表明，在氢化卵磷脂的相变温度下，膜的稳定性降低。利用双分子层的寿命值和测量的表面张力，与通过跨膜电流波动记录获得的实验数据相比，评估了跨膜孔的临界半径。结果表明，凝胶态双层脂质膜的寿命符合从杰里亚金-古托普-普罗霍罗夫理论推导的数据。对应于最大跨膜电流波动的孔半径接近凝胶态孔的临界值。
