Santos de Unamuno C, Llorente San Martín M A, Carandell Jäger E, Gutiérrez García M, Riera Jaume M, Ramírez Rosales A, Pareja Bezares A, Corrales Nadal A
Unidad Docente de Medicina Familiar y Comunitaria de Mallorca, Gerencia de Atención Primaria.
Med Clin (Barc). 1998 Mar 7;110(8):290-4.
It is not common that community-acquired pneumonias studies include patients non treated in hospital. The objectives were: to determine the cases managed in the ambulatory setting; to describe the clinical features; to identify the aetiological agents, and to describe the treatment, comparing inpatients with outpatients.
Observational prospective study. Population attended at three teaching primary care centers of Palma de Mallorca (60,450 habitants). Patients (> 14 years) were investigated when diagnosticated of community-acquired pneumoniae, from November 1992 to December 1994. Exclussions: HIV infection, patients living in a nursing home and tuberculosis. Data were collected in both Hospital and primary health care centers. Epidemiological, clinical, radiological and laboratory findings were recorded at the initial visit and 21 days after.
91 cases were investigated. 57% were managed at the primary care centers exclusively, 63.3% of the patients who went initially to the hospital were admitted in; but only 10.9% of those who went initially to the primary care centers (p < 0.005). 24 patients were hospitalized. 56 microbiological agents were identified in 48 patients (52.7%): Mycoplasma pneumoniae (10); Streptococcus pneumoniae (9); Influenza B (8); Chlamydia psittacci (7); Influenza A (7); Coxiella burnetii (5); Chlamydia pneumoniae (4); Legionella (3); Adenovirus (2); and Parainfluenza 3 (1). Mycoplasma was predominant in outpatients: 9 cases. S. pneumoniae in inpatients: 5 cases. Eritromycin was the most common treatment prescribed (76.9% of patients), alone or in combination with other antibiotics. Monotherapy was most common at primary care yield (96.7%) than at the hospital (45.2%) (p < 0.005).
Most of the patients with community-acquired pneumonias are managed at primary health care centers. M. pneumoniae is the predominant microbiological agent in outpatients and S. pneumoniae in inpatients. Erithromycin is the most used antibiotic in both groups of patients.
社区获得性肺炎研究纳入未住院治疗患者的情况并不常见。研究目的如下:确定在门诊治疗的病例;描述临床特征;识别病原体,并描述治疗情况,同时对住院患者和门诊患者进行比较。
前瞻性观察研究。研究对象为马略卡岛帕尔马市三个教学初级保健中心的人群(60450名居民)。1992年11月至1994年12月期间,对诊断为社区获得性肺炎的14岁以上患者进行调查。排除标准:HIV感染、住在疗养院的患者和结核病患者。在医院和初级卫生保健中心收集数据。在初次就诊时和21天后记录流行病学、临床、放射学和实验室检查结果。
共调查91例患者。57%仅在初级保健中心接受治疗,最初前往医院的患者中有63.3%被收治入院;但最初前往初级保健中心的患者中只有10.9%入院(p<0.0)。24例患者住院治疗。48例患者(52.7%)中鉴定出56种微生物病原体:肺炎支原体(10例);肺炎链球菌(9例);乙型流感(8例);鹦鹉热衣原体(7例);甲型流感(7例);伯纳特立克次体(5例);肺炎衣原体(4例);军团菌(3例);腺病毒(2例);副流感病毒3型(1例)。支原体在门诊患者中占主导:9例。肺炎链球菌在住院患者中占主导:5例。红霉素是最常用的处方药物(76.9%的患者),单独使用或与其他抗生素联合使用。单药治疗在初级保健机构中最为常见(96.7%),高于医院(45.2%)(p<0.005)。
大多数社区获得性肺炎患者在初级卫生保健中心接受治疗。门诊患者中肺炎支原体是主要病原体,住院患者中肺炎链球菌是主要病原体。红霉素是两组患者中最常用的抗生素。