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[腹膜假黏液瘤的临床与治疗考量]

[Clinical and therapeutic considerations in pseudomyxoma peritonei].

作者信息

Constantinoiu S, Chiru F, Mateş I N, Pop D, Cochior D, Bârlă R, Dinu D, Predescu D, Predescu V

机构信息

Clinica de Chirurgie, Spitalul Clinic Sfânta Maria, UMF Carol Davila, Bucureşti, România.

出版信息

Chirurgia (Bucur). 1998 Jan-Feb;93(1):27-37.

PMID:9567459
Abstract

Pseudomyxoma peritonei (PMP) is an uncommon clinical entity, lacking a precisely defined etiopathogenesis. Its clinical features are not specific and diagnosis is difficult. We analysed 10 patients, all of them women, whom we had treated surgically in combination with intraperitoneal chemotherapy. Postoperative complications had been minimal and no death had occurred. 5 patients were followed up in time, 4 of them presenting a favourable evolution (2 required reintervention), and 1 patient decreased. We analysed up-to-date therapeutic approaches and the benefit of their combinations in order to identify the optimal therapeutic strategy. We consider that the combinations surgery + intraperitoneal chemotherapy or surgery + intracavitary radiotherapy are the most effective up to date.

摘要

腹膜假黏液瘤(PMP)是一种罕见的临床病症,其病因发病机制尚无精确界定。其临床特征不具特异性,诊断困难。我们分析了10例患者,均为女性,我们对其进行了手术联合腹腔内化疗治疗。术后并发症极少,无死亡病例。5例患者进行了及时随访,其中4例病情进展良好(2例需要再次干预),1例病情恶化。我们分析了最新的治疗方法及其联合应用的益处,以确定最佳治疗策略。我们认为,目前手术+腹腔内化疗或手术+腔内放疗的联合应用是最有效的。

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