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[能否将核内DNA成像分析视为结直肠癌分期的一个新参数?]

[Is it possible to consider intranuclear DNA imaging analysis as a new parameter in the staging of colorectal cancer?].

作者信息

Midiri G, Giovagnoli M R, Tesoriere A, Giarnieri E, Covotta L, Bertolotti A, Vecchione A, Di Paola M

机构信息

Cattedra di IV Semeiotica Chirurgica, Università degli Studi La Sapienza, Roma.

出版信息

G Chir. 1998 Jan-Feb;19(1-2):9-12.

PMID:9567488
Abstract

Intranuclear DNA imaging may be considered as a marker of the biological behaviour of neoplasias. However, some questions fundamentally related to the interpretation of cytometric data, to the correlation with other histomorphological parameters and to tissue sampling concerning staging and prognostic evaluation of colon cancer patients are still unsolved. A way to solve this problem may be to perform multiple full thickness samplings.

摘要

核内DNA成像可被视为肿瘤生物学行为的一个标志物。然而,一些与细胞计量数据的解读、与其他组织形态学参数的相关性以及与结肠癌患者分期和预后评估相关的组织取样等根本相关的问题仍未得到解决。解决这个问题的一种方法可能是进行多次全层取样。

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