Lemma F, Chillemi S, Torchia U, Querci A, Geraci O, Milici M
Divisione di Oncologia Chirurgica, Cattedra di Chirurgia Generale C.L.O., Università degli Studi di Messina.
G Chir. 1998 Jan-Feb;19(1-2):41-3.
The different surgical options for the treatment of non toxic nodular goiter led the Authors to study the residual thyroid function following conservative surgery (subtotal thyroidectomy, lobectomy and enucleation). Follow-up showed an overall recurrence rate of 49%, with a higher rate after lobectomy and enucleation than after subtotal thyroidectomy. On the other hand, subclinical hypothyroidism was higher in patients who underwent subtotal thyroidectomy. No significative correlation was found between high plasmatic levels of TSH and recurrences.
治疗非毒性结节性甲状腺肿的不同手术选择促使作者研究保守手术后（甲状腺次全切除术、叶切除术和摘除术）的残余甲状腺功能。随访显示总体复发率为49%，叶切除术和摘除术后的复发率高于甲状腺次全切除术后。另一方面，接受甲状腺次全切除术的患者亚临床甲状腺功能减退的发生率更高。未发现血浆促甲状腺激素水平升高与复发之间存在显著相关性。
