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脑瘫与癫痫的关联。

Association of cerebral palsy with epilepsy.

作者信息

Kaushik A, Agarwal R P

机构信息

Department of Paediatrics, MLB Medical College, Jhansi.

出版信息

J Indian Med Assoc. 1997 Oct;95(10):552-4, 565.

PMID:9567601
Abstract

Fifty patients of various types of cerebral palsy were studied to find out an association between cerebral palsy, EEG abnormalities and development quotient. Seventy-six per cent patients had spastic cerebral palsy. Hypotonic cerebral palsy was the next common type (14%). Athetosis and ataxic forms were found to be rare (2% each). Epilepsy was associated with 56% patients. Clinical types of seizures observed were: Generalised tonic-clonic (43%), myoclonic (17.9%), generalised tonic (10.7%), partial simple (10.7%) and partial complex (17.9%). The incidence of seizures was highest in hypotonic type in which 85.7% had epilepsy. Mean developmental quotient of cerebral palsy patients was 34.9% with maximum retardation in hypotonic cerebral palsy (25.14%). Sixty per cent of patients had abnormal EEG, out of these hypotonic patients had maximum (70%) chances of EEG abnormality followed by spastic patients (55%). Developmental retardation was more severe statistically in the patients with abnormal EEG than normal EEG.

摘要

对50名不同类型的脑瘫患者进行了研究,以找出脑瘫、脑电图异常与发育商之间的关联。76%的患者为痉挛型脑瘫。低张型脑瘫是第二常见的类型(14%)。发现手足徐动型和共济失调型较为罕见(各占2%)。56%的患者伴有癫痫。观察到的临床癫痫类型有:全身强直阵挛性发作(43%)、肌阵挛发作(17.9%)、全身强直性发作(10.7%)、部分性单纯发作(10.7%)和部分性复杂发作(17.9%)。癫痫发病率在低张型中最高,其中85.7%患有癫痫。脑瘫患者的平均发育商为34.9%,低张型脑瘫患者的发育迟缓最为严重(25.14%)。60%的患者脑电图异常,其中低张型患者脑电图异常的几率最高(70%),其次是痉挛型患者(55%)。脑电图异常的患者在统计学上比脑电图正常的患者发育迟缓更严重。

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