Ma W Y, Ortalli I, Pedrazzi G, Vaccari S, Carlo-Stella C
Istituto di Scienze Fisiche, University of Parma, Italy.
Anticancer Res. 1998 Jan-Feb;18(1A):419-23.
Bone marrow cells collected from normal donors and from patients with chronic myelogenous leukemia (CML) and cultures of the K562 leukaemic cell line, were investigated after treatment with hematin and low-energy gamma rays from a 57Co Mössbauer source. Different degrees of growth inhibition were observed for bone marrow cultures and for the leukaemic cell line K562. Exposure to light irradiation during sample treatments was also investigated. The results seem promising and it is author's belief that cell inactivation by Mössbauer effect could have future applications in the field of tumor pathology as an alternative to or in the support of conventional radiotherapy.
对从正常供体和慢性粒细胞白血病（CML）患者采集的骨髓细胞以及K562白血病细胞系的培养物，在用来自57Co穆斯堡尔源的血红素和低能伽马射线处理后进行了研究。观察到骨髓培养物和白血病细胞系K562有不同程度的生长抑制。还研究了样品处理过程中暴露于光照射的情况。结果似乎很有前景，作者认为，穆斯堡尔效应导致的细胞失活在肿瘤病理学领域未来可能有应用，可作为传统放射治疗的替代方法或对其提供支持。
