Montes M A, DiNisco S, Dry S, Galvanek E
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Acta Cytol. 1998 Mar-Apr;42(2):396-8. doi: 10.1159/000331625.
Blastomyces dermatitidis is a dimorphic fungus; its usual port of entry is the lung. Although any organ system can be secondarily involved, non-pulmonary sites of primary infection have been reported.
This is the first reported case of primary isolated splenic B dermatitidis. The diagnostic value of fine needle aspiration cytology was examined by comparing it with the only previously reported case of primary (not isolated) splenic B dermatitidis.
In patients with splenic involvement by B dermatitidis, cytologic evaluation can be prompt and diagnostic. FNA biopsy in patients with splenomegaly is safe and well tolerated.
皮炎芽生菌是一种双相真菌；其通常的侵入途径是肺部。尽管任何器官系统都可能继发受累，但原发性感染的非肺部部位已有报道。
这是首例原发性孤立性脾脏皮炎芽生菌病的报道病例。通过与之前唯一报道的原发性（非孤立性）脾脏皮炎芽生菌病病例进行比较，研究了细针穿刺细胞学检查的诊断价值。
对于皮炎芽生菌累及脾脏的患者，细胞学评估可迅速做出诊断。脾肿大患者进行细针穿刺活检是安全的，且耐受性良好。
