膀胱乳头状尿路上皮癌在涂片上可见显著的印戒细胞。病例报告。

Papillary urothelial carcinoma of the urinary bladder demonstrating prominent signet-ring cells in a smear. A case report.

作者信息

Shinagawa T, Tadokoro M, Abe M, Koshitaka Y, Kouno S, Hoshino T

机构信息

Department of Pathology, St. Marianna University School of Medicine, Yokohama City Seibu Hospital, Japan.

出版信息

Acta Cytol. 1998 Mar-Apr;42(2):407-12. doi: 10.1159/000331628.

DOI:10.1159/000331628

PMID:9568147

Abstract

BACKGROUND

The appearance of numerous signetring cells (SRCs) without any other type of adenocarcinoma cells originating in papillary transitional cell carcinoma (TCC) in a urine smear is rare.

CASE

The cytology from mucus-urine that was initially obtained by washing from a 69-year-old female revealed three different types of cells: (1) numerous single SRC carcinoma-type cells, (2) low grade TCC-type cells arranged in sheets, and (3) intermediate (transitional)-type cells with both aspects of TCC and adenocarcinoma (SRC carcinoma) and mucus in the background. The latter two cell populations were retrospectively confirmed after histologic diagnosis of a primary papillary TCC with glandular differentiation.

CONCLUSION

One should keep in mind that even a low grade papillary TCC with glandular differentiation of the bladder can exhibit excessive SRC-type cells in urine.

摘要

背景

在尿液涂片中，源自乳头状移行细胞癌（TCC）的大量印戒细胞（SRC）出现而无任何其他类型腺癌细胞的情况很少见。

病例

最初通过对一名69岁女性的尿液进行冲洗获得的黏液尿细胞学检查显示出三种不同类型的细胞：（1）大量单个SRC癌类型细胞，（2）成片排列的低级别TCC类型细胞，以及（3）具有TCC和腺癌（SRC癌）两方面特征且背景中有黏液的中间（移行）型细胞。在对伴有腺性分化的原发性乳头状TCC进行组织学诊断后，回顾性确认了后两种细胞群。