Bhagavan H N, Coursin D B
J Nutr Sci Vitaminol (Tokyo). 1976;22(2):79-87. doi: 10.3177/jnsv.22.79.
The in vivo utilization of D[U-14C]glucose with particular reference to its incorporation into brain and liver proteins was studied in biotin-deficient rats. The data show a significant reduction in the incorporation of glucose carbon into brain and liver proteins. A disturbance in the intermediary metabolism of glucose to be one of the factors responsible for the decreased incorporation of the label into proteins in biotin deficiency.
在生物素缺乏的大鼠中研究了D-[U-¹⁴C]葡萄糖的体内利用情况,特别关注其掺入脑和肝蛋白质中的情况。数据显示,葡萄糖碳掺入脑和肝蛋白质的量显著减少。葡萄糖中间代谢的紊乱是生物素缺乏时标记物掺入蛋白质减少的原因之一。