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周期性人类子宫内膜中的萎缩与凋亡

Atrophy and apoptosis in the cyclical human endometrium.

作者信息

Hopwood D, Levison D A

出版信息

J Pathol. 1976 Jul;119(3):159-66. doi: 10.1002/path.1711190305.

DOI:10.1002/path.1711190305
PMID:956955
Abstract

Electron microscopy of human cyclical endometrium indicates that there is considerable loss of gland epithelial cells with formation of apoptotic bodies in the late secretory, premenstrual and menstrual phases, but also to a lesser extent in the proliferative phase. Apoptotic bodies containing nuclear fragments may be recognised on light microscopy as basophilic or Feulgen positive granules. These granules accumulate in greatest numbers towards the end of the cycle and may be used as an additional aid in dating curettings.

摘要

对人类周期性子宫内膜进行电子显微镜检查表明,在分泌晚期、经前期和月经期,腺上皮细胞大量丢失并形成凋亡小体,不过在增殖期也有少量出现。含有核碎片的凋亡小体在光学显微镜下可被识别为嗜碱性或福尔根阳性颗粒。这些颗粒在月经周期末期数量最多,可作为确定刮宫标本时间的辅助依据。

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