Eronat C, Alpöz A R
Ege University, Faculty of Dentistry, Department of Pedodontics, Izmir, Türkiye.
J Marmara Univ Dent Fac. 1997 Sep;2(4):605-8.
The aim of the present study was to assess the efficiency of a 1% chlorhexidine-containing varnish (Cervitec, Vivadent, Liechtenstein) on the levels of Streptococcus mutans in saliva of patients with fixed orthodontic appliances using the Dentocult-SM (Vivadent, Liechtenstein) technique for the microbiological investigation. Eighty subjects participated in the study and, divided randomly into two equal groups in which one group was treated with the placebo varnish (Vivadent, Liechtenstein) for negative controls. Streptococcus mutans in saliva of the subject was sampled and enumerated by using the Dentocult-SM dip-slide technique for periods of one, two four and twelve weeks after a single varnish application. The results were evaluated statistically. After the chlorhexidine containing varnish treatment the levels of Streptococcus mutans in saliva were significantly reduced after one week (p < 0.01) and continued reduction for one month (p < 0.05). After twelve weeks Streptococcus mutans levels in saliva were given a relative increase. No significant suppression was found in the placebo group (p > 0.05). The results suggested that Cervitec varnish reduces salivary Streptococcus mutans levels and that the application should be repeated every 3 months to get antibacterial effect.
本研究的目的是采用Dentocult-SM（列支敦士登维瓦登特公司）技术进行微生物学调查，评估含1%氯己定的清漆（Cervitec，列支敦士登维瓦登特公司）对使用固定正畸矫治器患者唾液中变形链球菌水平的影响。80名受试者参与了本研究，随机分为两组，其中一组用安慰剂清漆（列支敦士登维瓦登特公司）进行阴性对照。在单次涂抹清漆后的1周、2周、4周和12周，使用Dentocult-SM浸片技术对受试者唾液中的变形链球菌进行采样和计数。对结果进行统计学评估。含氯己定清漆治疗后，唾液中变形链球菌水平在1周后显著降低（p<0.01），并持续降低1个月（p<0.05）。12周后，唾液中变形链球菌水平相对升高。安慰剂组未发现显著抑制作用（p>0.05）。结果表明，Cervitec清漆可降低唾液中变形链球菌水平，且应每3个月重复涂抹以获得抗菌效果。
