在广泛使用溶栓治疗和阿司匹林前后急性心肌梗死后的一年死亡率。来自瑞典哥德堡社区的经验。
One-year mortality after acute myocardial infarction prior to and after the implementation of a widespread use of thrombolysis and aspirin. Experiences from the community of Göteborg, Sweden.
作者信息
Herlitz J, Hartford M, Karlson B W, Dellborg M, Källström G, Karlsson T
机构信息
Division of Cardiology, Sahlgrenska University Hospital, Göteborg, Sweden.
出版信息
Cardiology. 1998 Mar;89(3):216-21. doi: 10.1159/000006790.
UNLABELLED
During 1 year of follow-up, we compared the mortality after acute myocardial infarction (AMI) prior to and after the introduction of a more widespread use of thrombolytic agents and aspirin.
STUDY PERIOD
Two periods (I = 1986-1987 and II = 1989-1990) were compared.
PATIENTS
All patients admitted to the coronary care units at the two city hospitals in the community of Goteborg who fulfilled the criteria for development of AMI participated in the evaluation.
RESULTS
The overall 1-year mortality rate was 27% [corrected] during period I and 23% during period II (NS). However, among patients up to 70 years of age, the mortality was reduced from 15 to 11% (p < 0.05), whereas among patients aged over 70 years the mortality remained almost unchanged (34 vs. 35%; NS).
CONCLUSION
The introduction of a more widespread use of thrombolytic agents and aspirin has not substantially changed the overall mortality in AMI. However, among younger patients, the mortality appears to have been reduced but not among the elderly.
未标注
在1年的随访期间，我们比较了在更广泛使用溶栓药物和阿司匹林之前及之后急性心肌梗死（AMI）后的死亡率。
研究时期
比较了两个时期（I = 1986 - 1987年和II = 1989 - 1990年）。
患者
哥德堡社区两家城市医院冠心病监护病房收治的所有符合AMI发病标准的患者参与了评估。
结果
I期1年总死亡率为27%[校正后]，II期为23%（无显著性差异）。然而，在70岁及以下患者中，死亡率从15%降至11%（p < 0.05），而在70岁以上患者中，死亡率几乎保持不变（34%对35%；无显著性差异）。
结论
更广泛地使用溶栓药物和阿司匹林并没有显著改变AMI的总体死亡率。然而，在年轻患者中，死亡率似乎有所降低，但老年患者中没有。
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