Maury W
Department of Microbiology, University of South Dakota School of Medicine, Vermillion 57069, USA.
J Biomed Sci. 1998;5(1):11-23. doi: 10.1007/BF02253351.
Equine infectious anemia virus (EIAV) is an ungulate lentivirus that is related to human immunodeficiency virus (HIV). Much of the understanding of lentiviral gene regulation comes from studies using HIV. HIV studies have provided insights into molecular regulation of EIAV expression; however, much of the regulation of EIAV expression stands in stark contrast to that of HIV. This review provides an overview of the current state of knowledge of EIAV regulation by comparing and contrasting EIAV gene regulation to HIV. The role of EIAV gene regulation is discussed in relation to EIAV pathogenesis.
马传染性贫血病毒（EIAV）是一种与人类免疫缺陷病毒（HIV）相关的有蹄类慢病毒。对慢病毒基因调控的许多理解来自于对HIV的研究。HIV研究为EIAV表达的分子调控提供了见解；然而，EIAV表达的许多调控与HIV的调控形成了鲜明对比。本综述通过比较和对比EIAV与HIV的基因调控，概述了EIAV调控的当前知识状态。讨论了EIAV基因调控在EIAV发病机制中的作用。
