与既往使用他莫昔芬治疗乳腺癌相关的低恶性潜能男性化卵巢肿瘤。
Virilizing ovarian tumor of low malignant potential associated with antecedent tamoxifen use for breast cancer.
作者信息
Surbek D V, Hoesli I, Torhorst J, Almendral A C, Dellas A, Holzgreve W
机构信息
Department of Obstetrics and Gynecology, University Hospital, Basel, Switzerland.
出版信息
Gynecol Oncol. 1998 Mar;68(3):293-6. doi: 10.1006/gyno.1998.4935.
A patient is described who was treated with tamoxifen for breast cancer and developed an androgen-producing ovarian tumor of low malignant potential, which itself is a rare condition. Clinically overt virilism was leading to the diagnosis and promptly improved after surgical removal of the tumor. A causal relationship between tamoxifen use and the tumor is discussed on the basis of the known tumor-inducing potential of tamoxifen.
本文描述了一名接受他莫昔芬治疗乳腺癌的患者，该患者发生了一种低恶性潜能的雄激素分泌性卵巢肿瘤，这本身就是一种罕见的情况。临床上明显的男性化表现促使了该肿瘤的诊断，并且在手术切除肿瘤后症状迅速改善。基于他莫昔芬已知的致瘤潜能，讨论了使用他莫昔芬与该肿瘤之间的因果关系。
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