Oplinger N L, Zaidman G W, Buxton D F
New York Medical College, Valhalla, USA.
Ophthalmic Surg Lasers. 1998 Apr;29(4):305-8.
To determine whether ensured graft acceptance through the use of corneal autografts yields a better outcome than when standard homografts are used.
Four patients who needed a corneal transplant in one eye and who had a blind fellow eye underwent a corneal autograft in the eye with corneal pathology.
Three of the four patients had clear grafts on long-term follow-up, and no patient experienced immunologic graft rejection. However, two of the four patients had large amounts of astigmatism postoperatively.
Autografts provided protection against immunologic graft rejection. However, because corneal autografts yielded unpredictable amounts of astigmatism, their outcomes are not necessarily better than those of homografts.
确定通过使用角膜自体移植确保移植物接受是否比使用标准同种异体移植产生更好的结果。
4例单眼需要角膜移植且对侧眼失明的患者,对患角膜病变的眼进行了角膜自体移植。
4例患者中有3例在长期随访中移植片保持透明,无患者发生免疫性移植排斥反应。然而,4例患者中有2例术后出现大量散光。
自体移植可防止免疫性移植排斥反应。然而,由于角膜自体移植产生的散光量不可预测,其结果不一定优于同种异体移植。