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角膜自体移植与同种异体移植的比较。

A comparison of corneal autografts with homografts.

作者信息

Oplinger N L, Zaidman G W, Buxton D F

机构信息

New York Medical College, Valhalla, USA.

出版信息

Ophthalmic Surg Lasers. 1998 Apr;29(4):305-8.

PMID:9571663
Abstract

BACKGROUND AND OBJECTIVE

To determine whether ensured graft acceptance through the use of corneal autografts yields a better outcome than when standard homografts are used.

PATIENTS AND METHODS

Four patients who needed a corneal transplant in one eye and who had a blind fellow eye underwent a corneal autograft in the eye with corneal pathology.

RESULTS

Three of the four patients had clear grafts on long-term follow-up, and no patient experienced immunologic graft rejection. However, two of the four patients had large amounts of astigmatism postoperatively.

CONCLUSION

Autografts provided protection against immunologic graft rejection. However, because corneal autografts yielded unpredictable amounts of astigmatism, their outcomes are not necessarily better than those of homografts.

摘要

背景与目的

确定通过使用角膜自体移植确保移植物接受是否比使用标准同种异体移植产生更好的结果。

患者与方法

4例单眼需要角膜移植且对侧眼失明的患者,对患角膜病变的眼进行了角膜自体移植。

结果

4例患者中有3例在长期随访中移植片保持透明,无患者发生免疫性移植排斥反应。然而,4例患者中有2例术后出现大量散光。

结论

自体移植可防止免疫性移植排斥反应。然而,由于角膜自体移植产生的散光量不可预测,其结果不一定优于同种异体移植。

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