van de Kerkhof P C
Department of Dermatology, University Hospital Nijmegen, Netherlands.
Neth J Med. 1998 Jan;52(1):40-5. doi: 10.1016/s0300-2977(97)00081-8.
A spectrum of treatments is available for patients with psoriasis. It is of utmost importance to individualize the selection of treatment for the individual patient at the very moment of consultation. The manifestation of psoriasis, the extent of the lesions and the subjective discomfort of psoriasis are important factors which denominate the selection of treatment. The most important topical treatments are calcipotriol, dithranol, tar and corticosteroids. If topical treatments are unsuccessful, phototherapy with UVB, photochemotherapy (PUVA), methotrexate, cyclosporin and acitretin are the most important therapeutical options. The possibilities and limitations of these treatments will be presented in this review. In particular, the question will be addressed to what extent treatments of psoriasis may have systemic complications.
有一系列治疗方法可供银屑病患者使用。在会诊时为个体患者个性化选择治疗方案至关重要。银屑病的表现、皮损范围以及银屑病带来的主观不适是决定治疗选择的重要因素。最重要的局部治疗药物有卡泊三醇、地蒽酚、焦油和皮质类固醇。如果局部治疗无效，紫外线B光疗、光化学疗法（补骨脂素加紫外线A，PUVA）、甲氨蝶呤、环孢素和阿维A是最重要的治疗选择。本综述将介绍这些治疗方法的可能性和局限性。特别是，将探讨银屑病治疗在多大程度上可能引发全身并发症的问题。
