Colacurci N, Zarcone R, de Franciscis P, Mele D, Mollo A, de Placido G
2nd Department of Gynecology and Obstetrics, School of Medicine, Second University of Naples, Italy.
Panminerva Med. 1998 Mar;40(1):45-7.
To evaluate operative course, tubal patency and reproductive performance after laparoscopic treatment of ectopic pregnancy in relation to initial human chorionic gonadotropin (hCG) values and to the kind of operation.
Retrospective study.
Fourty-five patients affected by ectopic pregnancies: thirty-two treated with laparoscopic linear salpingotomy subvided into two groups depending on the hCG serum values < 10,000 mUl/ml (twenty patients: group 1) or > 10,000 mUl/ml (twelve patients Group 2), thirteen patients (Group 3) undergoing laparoscopic salpingectomy. Hysterosalpingographic examination was performed two or three months after surgery.
Operative time, major surgical complications, tubal patency and pregnancy rate after surgery.
Operative time was significantly (p < 0.05) lower in both group 1 and 3 (22.5 +/- 3.2 and 19.1 +/- 6.3, respectively) than in group 2 (39.4 +/- 5.6). Bilateral patent tubes were observed in eighteen cases of group 1 (90%) and eight cases of group 2 (60%). No statistically significant differences were found between the pregnancy rate of both group 1 (8/18) and 2 (3/8) and of group 3 (3/11).
Reproductive outcome is similar in both conservative and destructive laparoscopic management of ectopic pregnancy: furthermore it shows a trend of improvement, not statistically significant, in conservative treatment.
评估腹腔镜治疗异位妊娠后的手术过程、输卵管通畅情况及生殖性能，分析其与初始人绒毛膜促性腺激素（hCG）值及手术方式的关系。
回顾性研究。
45例异位妊娠患者：32例行腹腔镜线性输卵管切开术，根据血清hCG值分为两组，hCG值<10,000 mUl/ml（20例：第1组）或>10,000 mUl/ml（12例：第2组）；13例（第3组）行腹腔镜输卵管切除术。术后两到三个月进行子宫输卵管造影检查。
手术时间、主要手术并发症、术后输卵管通畅情况及妊娠率。
第1组和第3组的手术时间（分别为22.5±3.2和19.1±6.3）显著低于第2组（39.4±5.6）（p<0.05）。第1组18例（90%）和第2组8例（60%）观察到双侧输卵管通畅。第1组（8/18）和第2组（3/8）以及第3组（3/11）的妊娠率之间未发现统计学显著差异。
腹腔镜保守性和破坏性治疗异位妊娠的生殖结局相似：此外，保守治疗显示出改善趋势，但无统计学显著性。
