Colacurci N, De Franciscis P, Zarcone R, Fortunato N, Passaro M, Mollo A, Russo G
Department of Gynecology and Obstetrics, School of Medicine, Second University of Naples, Italy.
Panminerva Med. 1998 Sep;40(3):223-5.
The aim of this study was to compare the time length until the human chorionic gonadotropin titer became negative after medical or surgical treatment of ectopic pregnancy.
Prospective, randomized study. PARTECIPANTS AND INTERVENTIONS: We compared time to resolution in 30 cases of tubal pregnancies successfully treated, 15 underwent laparoscopic linear salpingostomy (group 1) and 15 medical treatment with single-ose methotrexate (group 2). The patients of both groups had no meaningful differences of age, gestational age and human chorionic gonadotropin mean values.
During the follow-up human chorionic gonadotropin serum values were obtained every two days until the titer was negative.
The time to resolution was 33.6 +/- 6.6 days in group 1, 31.5 +/- 7.8 in group 2 with no statistically meaningful differences.
The data, comparable with results obtained by laparoscopic treatment, suggest that human chorionic gonadotropin value becomes negative independently of type of treatment and residual trophoblast.
本研究旨在比较异位妊娠经药物或手术治疗后，人绒毛膜促性腺激素水平降至阴性所需的时间。
前瞻性随机研究。
我们比较了30例成功治疗的输卵管妊娠患者的恢复时间，其中15例行腹腔镜线性输卵管造口术（第1组），15例采用单剂量甲氨蝶呤进行药物治疗（第2组）。两组患者在年龄、孕周和人绒毛膜促性腺激素平均值方面无显著差异。
在随访期间，每两天检测一次血清人绒毛膜促性腺激素值，直至其水平降至阴性。
第1组的恢复时间为33.6±6.6天，第2组为31.5±7.8天，差异无统计学意义。
这些数据与腹腔镜治疗的结果相当，表明人绒毛膜促性腺激素水平降至阴性与治疗方式及残留滋养层无关。
