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椎间盘疾病相关腰椎神经根病治疗中神经根周围皮质类固醇注射的短期评估

Short-term evaluation of periradicular corticosteroid injections in the treatment of lumbar radiculopathy associated with disc disease.

作者信息

Viton J M, Rubino T, Peretti-Viton P, Bouvenot G, Delarque A

机构信息

Neuroradiology Department, La Timone Teaching Hospital, Marseille, France.

出版信息

Rev Rhum Engl Ed. 1998 Mar;65(3):195-200.

PMID:9574477
Abstract

OBJECTIVES

The purpose of this study was to evaluate the feasibility and efficacy of periradicular corticosteroid injections performed under fluoroscopic guidance in the treatment of pain originating in the lumbosacral nerve roots.

METHOD

Forty patients presenting with lumbosciatica or femoral neuralgia unresponsive to conventional conservative treatment were admitted to the study. Patients with nerve root pain due to infectious, tumorous or inflammatory diseases were excluded, as were patients who needed immediate surgery. Pain was evaluated using a visual analog scale on the day of the injection and ten (D10) and ninety (D90) days later.

RESULTS

All patients were evaluated as scheduled on D10 and D90. The mean visual analog scale score decreased from 53.3 mm at baseline to 30.1 mm on D10 and to 21.8 mm on D90. Ninety per cent of patients had a visual analog pain score decrease on D10 and 85% on D90. Reported side effects were two cases of mild spontaneously regressive acne and one case of radicular pain exacerbation of less than one day's duration.

CONCLUSION

Periradicular injections of corticosteroids done under fluoroscopic guidance as an outpatient procedure was effective and safe in our study and may deserve to be used as part of the conservative management of lumbar nerve root pain before resorting to more invasive methods.

摘要

目的

本研究旨在评估在荧光镜引导下进行的神经根周围皮质类固醇注射治疗腰骶神经根源性疼痛的可行性和疗效。

方法

40例对传统保守治疗无反应的腰腿痛或股神经痛患者纳入本研究。排除因感染、肿瘤或炎症性疾病导致神经根疼痛的患者以及需要立即手术的患者。在注射当天、第10天(D10)和第90天(D90)使用视觉模拟量表评估疼痛程度。

结果

所有患者均在D10和D90按计划进行评估。视觉模拟量表平均评分从基线时的53.3毫米降至D10时的30.1毫米,D90时降至21.8毫米。90%的患者在D10时视觉模拟疼痛评分下降,85%的患者在D90时下降。报告的副作用为2例轻度自发消退的痤疮和1例持续时间不到一天的神经根疼痛加重。

结论

在我们的研究中,在荧光镜引导下作为门诊手术进行的神经根周围皮质类固醇注射是有效且安全的,在采用更具侵入性的方法之前,可能值得作为腰神经根疼痛保守治疗的一部分。

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