Yamataka A, Pringle K C, Wyeth J
Department of Surgery, Wellington School of Medicine, New Zealand.
J Pediatr Surg. 1998 Apr;33(4):660-2. doi: 10.1016/s0022-3468(98)90341-4.
Zinc chloride is a powerful corrosive agent. Reports of zinc chloride ingestion are uncommon, and there is little information about its toxicity and management. The authors report the clinical course of a 10-year-old girl who accidentally ingested an acid soldering flux solution (pH, 3.0; zinc chloride, 30% to < 60%). Systemic effects after the ingestion were unremarkable except for lethargy. Thus, chelation therapy was not considered. Severe gastric corrosion was caused by local caustic action. An antral stricture of the stomach approximately 3 weeks after the ingestion developed, and she underwent a modified Heineke-Mikulicz antropyloroplasty. Postoperatively, she made an uneventful recovery. On follow-up, although she was tolerating a normal diet, results of a barium meal showed her stomach to be totally aperistaltic. Results of a nuclear medicine study showed moderately delayed gastric emptying. Careful long-term follow-up is necessary, because there is potential risk for malignancy in the damaged stomach.
氯化锌是一种强腐蚀剂。关于摄入氯化锌的报道并不常见，且关于其毒性和处理方法的信息很少。作者报告了一名10岁女孩意外摄入酸性焊接助熔剂溶液（pH值为3.0；氯化锌含量为30%至<60%）后的临床过程。摄入后除嗜睡外，全身影响不明显。因此，未考虑螯合疗法。局部腐蚀作用导致严重的胃腐蚀。摄入后约3周出现胃窦狭窄，她接受了改良的海涅克-米库利奇胃窦幽门成形术。术后，她恢复顺利。随访时，尽管她能耐受正常饮食，但钡餐检查结果显示她的胃完全无蠕动。核医学研究结果显示胃排空中度延迟。由于受损胃部有发生恶性肿瘤的潜在风险，因此需要进行仔细的长期随访。
