Reid M C, Lane D A, Feinstein A R
Clinical Epidemiology Unit, VA Connecticut Healthcare System, West Haven 06516, USA.
Am J Med. 1998 Apr;104(4):374-80. doi: 10.1016/s0002-9343(98)00054-0.
To determine how often practicing physicians use the customarily recommended quantitative methods that include sensitivity, specificity, and likelihood ratio indexes; receiver operator characteristic (ROC) curves; and Bayesian diagnostic calculations.
A random sample of 300 practicing physicians (stratified by specialty to include family physicians, general internists, general surgeons, pediatricians, obstetrician/gynecologists, and internal medicine subspecialists) were briefly interviewed in a telephone survey. They were asked about the frequency with which they used the formal methods, the reasons for non-use, and if they employed alternative strategies when appraising tests' diagnostic accuracy.
Of the 300 surveyed physicians, 8 (3%) used the recommended formal Bayesian calculations, 3 used ROC curves, and 2 used likelihood ratios. The main reasons cited for non-use included impracticality of the Bayesian method (74%), and nonfamiliarity with ROC curves and likelihood ratios (97%). Of the 174 physicians who said they used sensitivity and specificity indexes, 165 (95%) did not do so in the recommended formal manner. Instead, the physicians directly estimated tests' diagnostic accuracy by determining how often the test results were correct in groups of patients later found to have, or to be free of, the selected disease.
The results indicate that most practicing physicians do not use the formal recommended quantitative methods to appraise tests' diagnostic accuracy, and instead report using an alternative direct approach. Although additional training might make physicians use the formal methods more often, the physicians' direct method merits further evaluation as a potentially pragmatic tool for the determination of tests' diagnostic accuracy in clinical practice.
确定执业医师使用包括敏感度、特异度和似然比指数等常用推荐定量方法、受试者操作特征(ROC)曲线以及贝叶斯诊断计算的频率。
通过电话调查对300名执业医师进行随机抽样(按专业分层,包括家庭医生、普通内科医生、普通外科医生、儿科医生、妇产科医生和内科专科医生)。询问他们使用这些正式方法的频率、不使用的原因,以及在评估检查的诊断准确性时是否采用替代策略。
在300名接受调查的医生中,8名(3%)使用了推荐的正式贝叶斯计算方法,3名使用了ROC曲线,2名使用了似然比。不使用的主要原因包括贝叶斯方法不实用(74%),以及不熟悉ROC曲线和似然比(97%)。在174名表示使用敏感度和特异度指数的医生中,165名(95%)并非以推荐的正式方式使用。相反,这些医生通过确定在后来被发现患有或未患有所选疾病的患者群体中检查结果正确的频率,直接估计检查的诊断准确性。
结果表明,大多数执业医师不使用推荐的正式定量方法来评估检查的诊断准确性,而是报告使用一种替代的直接方法。尽管额外的培训可能会使医生更频繁地使用正式方法,但医生的直接方法作为临床实践中确定检查诊断准确性的一种潜在实用工具,值得进一步评估。