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颈淋巴静脉分流术治疗腔静脉狭窄犬及肝硬化患者腹水。实验观察与7年临床经验。

Cervical lymphato-venous shunt in treatment of ascites in caval-constricted dogs and in patients with hepatic cirrhosis. Experimental observations and 7 years clinical experience.

作者信息

Serényi P, Magyar Z, Szabó G

出版信息

Lymphology. 1976 Jun;9(2):53-61.

PMID:957766
Abstract

In experimental ascites produced by inferior vena caval constriction there is a pressure gradient at the thoracic duct-venous junction suggesting a functional obstacle to lymph flow. Abdominal fluid and protein are transported mainly by the right lymph trunk and not by the thoracic duct. External drainage of the thoracic duct or construction of a new, wider thoracic duct-venous anastomosis facilitates, however, transport of excess capillary filtrate formed in the liver and decreases fluid spillage into the peritoneal cavity. Construction of a cervical lymphato-venous anastomosis was attempted in 21 patients, 20 of whom had cirrhosis, and the operation was technically successful in 16 cases. Operation was helpful in cirrhotic patients with rapid ascites formation, who required less frequent abdominal paracenteses operation. The shunt was without benefit in prevention of oesophageal varix bleedings, and it should not be attempted in patients with icterus and severe deterioration of liver function.

摘要

在下腔静脉缩窄所致的实验性腹水中,胸导管-静脉交界处存在压力梯度,提示淋巴流动存在功能性障碍。腹水和蛋白质主要通过右淋巴干而非胸导管运输。然而,胸导管的外部引流或构建新的、更宽的胸导管-静脉吻合术有利于肝脏中形成的过量毛细血管滤过液的运输,并减少液体漏入腹腔。对21例患者尝试进行颈淋巴管-静脉吻合术,其中20例患有肝硬化,16例手术在技术上成功。该手术对腹水形成迅速的肝硬化患者有帮助,这些患者需要较少频繁进行腹腔穿刺术。该分流术对预防食管静脉曲张出血无益处,且黄疸和肝功能严重恶化的患者不应尝试。

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