[白细胞介素6对人体子宫收缩力的体内效应]

[Effect of interleukin 6 on uterine contractility in the human in vivo].

作者信息

Lechner W, Bergant A, Marth C, Kirchler H, Zwierzina H

机构信息

Universitätsklinik für Frauenheilkunde, Innsbruck.

出版信息

Z Geburtshilfe Neonatol. 1998 Jan-Feb;202(1):10-3.

PMID:9577916

Abstract

The influence on uterine contractility of inflammatory cytokines like interleukin-6 is widely unknown. We were able to demonstrate in 16 human myometrial strips obtained during caesarean section in the organ chamber a highly significant (P < 0.001) increase of the activity of uterine strips after addition of IL-6. This further emphasizes the importance of subclinical infections for the etiology of so called idiopathic preterm labour.

摘要

白细胞介素 - 6等炎性细胞因子对子宫收缩力的影响尚不为人所知。我们在器官培养室剖宫产术中获取的16条人子宫肌条中证实，添加IL - 6后子宫肌条活性显著增强（P < 0.001）。这进一步强调了亚临床感染在所谓特发性早产病因中的重要性。