迟发性线粒体脑肌病伴乳酸血症和卒中样发作（MELAS）中的复杂部分性癫痫持续状态

Complex partial status epilepticus in late-onset MELAS.

作者信息

Leff A P, McNabb A W, Hanna M G, Clarke C R, Larner A J

机构信息

National Hospital for Neurology and Neurosurgery, London, England, UK.

出版信息

Epilepsia. 1998 Apr;39(4):438-41. doi: 10.1111/j.1528-1157.1998.tb01397.x.

DOI:10.1111/j.1528-1157.1998.tb01397.x

PMID:9578035

Abstract

A patient with recurrent episodes of complex partial status epilepticus and a distinctive pattern of periodic lateralized epileptiform discharges (PLEDs) is presented. The patient was subsequently shown to have a mitochondrial disorder of the MELAS type, a hitherto unreported association. The case illustrates that CPSE should be added to the list of possible causes of acute neurological deterioration in MELAS patients.

摘要

本文报告了一名患有复杂部分性癫痫持续状态反复发作且具有独特的周期性一侧性癫痫样放电（PLEDs）模式的患者。该患者随后被证实患有MELAS型线粒体疾病，这是一种迄今未报道过的关联。该病例表明，CPSE应被列入MELAS患者急性神经功能恶化的可能原因清单中。