药物递送与靶向
Drug delivery and targeting.
作者信息
Langer R
机构信息
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02139, USA.
出版信息
Nature. 1998 Apr 30;392(6679 Suppl):5-10.
PMID:9579855
Abstract
When a pharmaceutical agent is encapsulated within, or attached to, a polymer or lipid, drug safety and efficacy can be greatly improved and new therapies are possible. This has provided the impetus for active study of the design of degradable materials, intelligent delivery systems and approaches for delivery through different portals in the body.
摘要
当药物制剂被包裹在聚合物或脂质中，或附着于聚合物或脂质上时，药物的安全性和有效性可得到极大提高，新的治疗方法也成为可能。这为积极研究可降解材料的设计、智能给药系统以及通过体内不同途径给药的方法提供了动力。
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