Paz A, Sánchez-Andrade R, Díez-Baños P, Panadero R, Morrondo P
Department of Animal Pathology, Veterinary Faculty, Santiago de Compostela University, Lugo, Spain.
Folia Parasitol (Praha). 1998;45(1):53-6.
The variations in antibody responses (total IgG and IgG1, IgG2a, IgG2b, and IgG2c subclasses) were studied in two groups of rats infected with metacercariae of the trematode Fasciola hepatica L. Animals of group 1 were 4 weeks old, and rats of group 2 were 13 weeks old. All IgG subclasses increased during the course of infection except IgG2c, which decreased. The younger rats reached more marked responses than the older, at least during the period of this trial. IgG1 and IgG2a antibodies reached the highest levels, and among these two, IgG2a response was slightly superior to IgG1.
在两组感染肝片形吸虫尾蚴的大鼠中研究了抗体反应（总IgG以及IgG1、IgG2a、IgG2b和IgG2c亚类）的变化。第1组动物为4周龄，第2组大鼠为13周龄。除IgG2c降低外，所有IgG亚类在感染过程中均升高。至少在本试验期间，年幼大鼠的反应比年长大鼠更明显。IgG1和IgG2a抗体达到最高水平，在这两者中，IgG2a反应略优于IgG1。
