Domingo Triadó V, Bovaira Forner M, Viñoles Pérez J M, Cabezudo de la Muela L, Negueroles Albuixech D, Moro Blázquez B
Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Hospital Lluís Alcanyís, Xàtiva, Valencia.
Rev Esp Anestesiol Reanim. 1998 Feb;45(2):72-4.
We review the use of urapidil to manage hypertension in two patients undergoing adrenalectomy for pheochromocytoma and aldosterone producing adenoma. Bolus administration (25 mg/i.v.) of urapidil provided good control of blood pressure during surgical manipulation of the tumor, although continuous perfusion of the drug was required by one patient before complete excision was achieved. No changes in heart rate or sudden decrease in blood pressure were observed. We believe that urapidil may be useful for treating hypertension during tumor adrenalectomy.
我们回顾了乌拉地尔在两名因嗜铬细胞瘤和醛固酮分泌腺瘤接受肾上腺切除术患者中用于控制高血压的情况。乌拉地尔静脉推注（25毫克/次）在肿瘤手术操作期间能很好地控制血压，不过有一名患者在完全切除肿瘤之前需要持续输注该药物。未观察到心率变化或血压突然下降。我们认为乌拉地尔可能有助于在肾上腺肿瘤切除术中治疗高血压。
