Pinhas-Hamiel O, Barak Y, Siev-Ner I, Achiron A
Multiple Sclerosis Center, Sheba Medical Center, Tel-Hashomer, Israel.
J Pediatr. 1998 Apr;132(4):735-7. doi: 10.1016/s0022-3476(98)70371-3.
In a retrospective study we analyzed clinical features and their prognostic significance in 72 patients with onset of multiple sclerosis by the age of 21 years. In juvenile multiple sclerosis disease progression does not depend on age of onset, severity of neurologic involvement, or polysymptomatic or monosymptomatic involvement at presentation.
在一项回顾性研究中,我们分析了72例21岁前发病的多发性硬化症患者的临床特征及其预后意义。在青少年型多发性硬化症中,疾病进展并不取决于发病年龄、神经受累的严重程度,也不取决于起病时多症状或单症状受累情况。