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人类黄体功能的调控

Control of the luteal function in humans.

作者信息

Nakano R

机构信息

Department of Obstetrics and Gynecology, Wakayama Medical College, Japan.

出版信息

Semin Reprod Endocrinol. 1997;15(4):335-44. doi: 10.1055/s-2008-1068371.

DOI:10.1055/s-2008-1068371
PMID:9580942
Abstract

Although luteinizing hormone (LH) of the anterior pituitary is considered primarily responsible for the initiation of luteinization in most species, the mechanisms governing the subsequent life and death of the corpus luteum vary among species. In women and in nonhuman primate, the corpus luteum derives its support from LH that must be continuously present. To date, the factors regulating the life span and endocrine activity of the corpus luteum in humans and primates are not completely understood. This article summarizes our study on luteinizing hormone and chorionic gonadotropin receptors in human corpora lutea during the menstrual cycle and pregnancy and the apoptosis of human corpora lutea during the menstrual cycle and pregnancy.

摘要

虽然垂体前叶的促黄体生成素(LH)被认为是大多数物种中黄体化启动的主要原因,但黄体随后的生存和死亡机制在不同物种间存在差异。在女性和非人类灵长类动物中,黄体依赖于必须持续存在的LH来维持。迄今为止,调节人类和灵长类动物黄体寿命和内分泌活性的因素尚未完全明确。本文总结了我们关于月经周期和孕期人黄体中促黄体生成素和绒毛膜促性腺激素受体的研究,以及月经周期和孕期人黄体的凋亡情况。

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1
Control of the luteal function in humans.人类黄体功能的调控
Semin Reprod Endocrinol. 1997;15(4):335-44. doi: 10.1055/s-2008-1068371.
2
In vivo responses of the primate corpus luteum to luteinizing hormone and chorionic gonadotropin.灵长类动物黄体对促黄体生成素和绒毛膜促性腺激素的体内反应。
Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):11002-7. doi: 10.1073/pnas.95.18.11002.
3
[Studies on luteinizing hormone receptors of human corpora lutea during menstrual cycle and pregnancy].
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Gonadotropin binding sites in human ovarian follicles and corpora lutea during the menstrual cycle.月经周期中人类卵巢卵泡和黄体中的促性腺激素结合位点。
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Corpus luteum development: lessons from genetic models in mice.黄体发育:来自小鼠遗传模型的经验教训。
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Expression of LGR7 in the primate corpus luteum implicates the corpus luteum as a relaxin target organ.灵长类动物黄体中LGR7的表达表明黄体是松弛素的靶器官。
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Endocrine and paracrine-autocrine regulation of the human corpus luteum during the mid-luteal phase.黄体中期人黄体的内分泌及旁分泌-自分泌调节
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