Rudenko G, Cross M, Borst P
Dept of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Trends Microbiol. 1998 Mar;6(3):113-6. doi: 10.1016/s0966-842x(97)01200-6.
African trypanosomes express the gene encoding their variant surface glycoprotein (VSG) surface coat from one of many telomeric expression sites. This genomic location at chromosome ends not only allows easy exchange of VSG gene cassettes using various mechanisms of DNA recombination but also appears to play a role in VSG gene expression site control.
非洲锥虫从众多端粒表达位点之一表达编码其可变表面糖蛋白（VSG）表面 coat 的基因。染色体末端的这个基因组位置不仅允许使用各种 DNA 重组机制轻松交换 VSG 基因盒，而且似乎在 VSG 基因表达位点控制中发挥作用。
