Schütz H, Erdmann F, Magiera E S, Weiler G
Institut für Rechtsmedizin, Universität Giessen.
Arch Kriminol. 1998 Mar-Apr;201(3-4):93-6.
Numerous urine samples were found to be positive when using a new amphetamine immunoassay (AxSYM). Confirmation analysis was carried out in a second laboratory at "reasonable prices" using a simple TLC-method with non specific ninhydrine detection and resulted in many "positive" confirmation findings. The GC/MS analysis clearly indicated the absence of amphetamine derivatives regularly encountered in forensic toxicology. The false-positive immunochemical findings may probably be caused by endogenous substances.
使用一种新型苯丙胺免疫分析法(AxSYM)时,发现大量尿液样本呈阳性。在另一家实验室以“合理价格”采用简单的薄层色谱法并使用非特异性茚三酮检测法进行确证分析,结果得出许多“阳性”确证结果。气相色谱/质谱分析清楚地表明,法医毒理学中常见的苯丙胺衍生物并不存在。免疫化学检测结果出现假阳性可能是由内源性物质引起的。