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[术前分期作为胃癌治疗决策依据的准确性如何?]

[How accurate is preoperative staging as a basis for treatment decisions in gastric carcinoma?].

作者信息

Heyer T, Frieling T, Häussinger D

机构信息

Klinik für Gastroenterologie, Hepatologie und Infektiologie, Heinrich-Heine-Universität, Düsseldorf.

出版信息

Praxis (Bern 1994). 1998 Mar 25;87(13):443-6.

PMID:9584569
Abstract

The treatment of advanced gastric carcinoma by various neoadjuvant and adjuvant multimodal therapy regimes is under current investigation to improve the poor outcome of these patients. Therefore, pretherapeutic tumor staging according to the TNM classification is essential for the optimal application of various therapeutic modalities. According to recent studies, endoscopic ultrasonography (EUS) is the most sensitive technique in measuring tumor infiltration (T-staging). In addition, although less reliable compared to the T-staging, the sensitivity of EUS in assessing lymph node status (N-staging) is superior to computed tomography and conventional ultrasound. Pretherapeutic laparoscopic investigation may give additional important information about tumor stage. This overview describes the significance of various diagnostic techniques that can be applied in tumor staging investigations.

摘要

目前正在研究采用各种新辅助和辅助多模式治疗方案来治疗晚期胃癌,以改善这些患者的不良预后。因此,根据TNM分类进行治疗前肿瘤分期对于各种治疗方式的最佳应用至关重要。根据最近的研究,内镜超声检查(EUS)是测量肿瘤浸润(T分期)最敏感的技术。此外,尽管与T分期相比可靠性稍低,但EUS评估淋巴结状态(N分期)的敏感性优于计算机断层扫描和传统超声。治疗前的腹腔镜检查可能会提供有关肿瘤分期的其他重要信息。本综述描述了可应用于肿瘤分期检查的各种诊断技术的意义。

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引用本文的文献

1
Diagnostic accuracy of endoscopic ultrasonography (EUS) for the preoperative locoregional staging of primary gastric cancer.内镜超声检查(EUS)对原发性胃癌术前局部区域分期的诊断准确性。
Cochrane Database Syst Rev. 2015 Feb 6;2015(2):CD009944. doi: 10.1002/14651858.CD009944.pub2.
2
Does endoscopic ultrasound staging already allow individual treatment regimens in gastric cancer.内镜超声分期是否已能确定胃癌的个体化治疗方案?
Wien Klin Wochenschr. 2006;118 Suppl 2:48-51. doi: 10.1007/s00508-006-0552-y.
3
Endoscopic ultrasonography in preoperative staging of gastric cancer: determination of tumor invasion depth, nodal involvement and surgical resectability.
内镜超声检查在胃癌术前分期中的应用:确定肿瘤浸润深度、淋巴结受累情况及手术可切除性。
World J Gastroenterol. 2003 Feb;9(2):254-7. doi: 10.3748/wjg.v9.i2.254.