Majkowski J
Neurol Neurochir Pol. 1976 Jul-Aug;10(4):447-56.
On the basis of personal investigations including 1) electrophysiological methods (EEG, averaged evoked potentials), 2) behavior methods, 3) destruction of various parts of the brain (mesencephalic reticular formation, auditory pathways) and 4) pharmacological methods, conducted in the years 1953-1974 the author put forward a concept of sensory organization of reticular formation postulating existence of special systems in the reticular formation differing in their relative physiological and chemical specificity. This relative specificity is, in this concept, the ability of the so-called non-specific neurons in the reticular formation to be included under certain experimental conditions into specific functional systems. The author suggests the term "paraspecific systems" for designating these relatively specific systems. It seems that these systems determine the integrative role of reticular formation in the process of learning. In contrast to this important role the reticular formation is without any greater importance for the process of memory storage. The dynamic and relatively specific functional organization of reticular formation provides potential possibilities of its utilization in the processes of reeducation or rehabilitation in central nervous system damage and in pharmacological treatment of psychic disturbances.
基于1953年至1974年间进行的个人研究,包括:1)电生理方法(脑电图、平均诱发电位);2)行为方法;3)破坏大脑的各个部分(中脑网状结构、听觉通路);4)药理学方法,作者提出了网状结构感觉组织的概念,假定网状结构中存在相对生理和化学特异性不同的特殊系统。在这一概念中,这种相对特异性是指网状结构中所谓的非特异性神经元在某些实验条件下能够被纳入特定功能系统的能力。作者建议用“副特异性系统”一词来指代这些相对特异性的系统。这些系统似乎决定了网状结构在学习过程中的整合作用。与这一重要作用形成对比的是,网状结构对记忆存储过程没有太大重要性。网状结构动态且相对特异性的功能组织为其在中枢神经系统损伤的再教育或康复过程以及精神障碍的药物治疗中的应用提供了潜在可能性。