Detection of 2'-deoxyoxanosine by capillary electrophoresis.

We have investigated capillary electrophoresis separation of oxanine (Oxa), a base moiety of 2'-deoxyoxanosine (Figure 1), from various bases. Oxa was not well separated from the others by micelle electrokinetic chromatography which is a general method for separating of the bases. On the other hand, capillary zone electrophoresis showed much improved separation when used pH 12 where the six-membered ring of Oxa is opened.