Ramírez-Gaitán J L, Sánchez-Valdivieso E A, Soto-Pérez G, Muñóz-González D E
División de Servicios Paramédicos y Consulta Externa, Instituto Nacional de Cancerología, México.
Ginecol Obstet Mex. 1998 Feb;66:41-7.
From 1980 to 1991 were received 6,295 patients diagnosed as invasive cervical cancer at the Instituto Nacional de Cancerología of México; from this group, 884 cases were considered as stage IB (12.76%) and 133 cases, adenocarcinoma in 10, adenosquamous carcinoma in 6 and minimal deviation adenocarcinoma (malignant adenoma) in one case. Eighty percent of cases had a less than 2 cm tumor size. Thirteen cases had metastatic pelvic lymph nodes. Mean age 46 years (range 28-64 years), mean operatory time 4:50 hours (range 3-15 hours), average of hemorrhage 1,500 ml (range 300 to 5,000 ml). One patient died from no related cause. Bladder malfunction was observed in 8.4% and uro-vaginal fistula in 6.9% of the cases. Thirteen patients experimented tumor relapsing after 8 to 22 months of follow up. Only 3 out of 7 from that with tumor relapsing were saved with whole pelvic radiotherapy. One hundred-fifteen patients are alive and well after 63 months mean follow-up. Radical hysterectomy plus bilateral lymphadenectomy is an optimal surgical procedure in managing early invasive carcinoma of the cervix uteri.
1980年至1991年期间，墨西哥国家癌症研究所共收治了6295例被诊断为浸润性宫颈癌的患者；在这组患者中，884例被视为IB期（12.76%），其中133例为腺癌（10例）、腺鳞癌（6例）以及1例微小偏离腺癌（恶性腺瘤）。80%的病例肿瘤大小小于2厘米。13例出现盆腔淋巴结转移。平均年龄46岁（范围28 - 64岁），平均手术时间4小时50分钟（范围3 - 15小时），平均失血量1500毫升（范围300至5000毫升）。1例患者死于无关原因。8.4%的病例出现膀胱功能障碍，6.9%的病例出现膀胱阴道瘘。13例患者在随访8至22个月后出现肿瘤复发。复发的7例患者中只有3例通过全盆腔放疗得以挽救。平均随访63个月后，115例患者存活且状况良好。根治性子宫切除术加双侧淋巴结清扫术是治疗早期子宫颈浸润癌的最佳手术方式。
