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[急性胰腺炎与人类免疫缺陷病毒感染]

[Acute pancreatitis and infection with the human immunodeficiency virus].

作者信息

Sánchez Muñoz L A, Ferrero Beneitez O L, Pérez Boillos M J, Muñoz Sánchez J, Teira Cobo R, Baraia-Etxaburu J, Zubero Sulibarría Z, Santamaría Jáuregui J M

机构信息

Sección de Enfermedades Infecciosas, Hospital de Basurto, Bilbao, Vizcaya.

出版信息

Rev Clin Esp. 1998 Mar;198(3):133-9.

PMID:9586434
Abstract

BACKGROUND

Retrospective study of the etiology and evolution of 40 episodes of acute pancreatitis in 28 patients infected with the human immunodeficiency virus (HIV).

RESULTS

AIDS criteria were met by 89.3% of patients. The likely etiology was an opportunist infection in 32.5% of episodes, drug use in 22.5%, and biliary lithiasis in 5%. AP secondary to AIDS-associated cholangitis occurred in 35.7% of episodes. Sixty percent of episodes were severe in nature. The mortality rate reached 30%.

CONCLUSIONS

AP in HIV infected patients: a) is more frequent in the advanced stages of disease; b) opportunistic infections and drugs are the most frequent causes in our environment; c) in a third of patients it is probably secondary to AIDS associated cholangitis; d) biliary lithiasis seems to be less common than in the general population, and e) it is associated with a high severity and mortality.

摘要

背景

对28例感染人类免疫缺陷病毒(HIV)的患者中40次急性胰腺炎发作的病因及演变进行回顾性研究。

结果

89.3%的患者符合艾滋病标准。可能的病因是32.5%的发作由机会性感染引起,22.5%由药物使用引起,5%由胆石症引起。35.7%的发作是继发于艾滋病相关胆管炎的急性胰腺炎。60%的发作本质上是严重的。死亡率达到30%。

结论

HIV感染患者的急性胰腺炎:a)在疾病晚期更常见;b)在我们的研究环境中,机会性感染和药物是最常见的病因;c)三分之一的患者可能继发于艾滋病相关胆管炎;d)胆石症似乎比普通人群中少见,且e)与高严重程度和死亡率相关。

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