Rubio C A, Söderberg G, Grant C A, Chi C, Krepler R
Pathol Eur. 1976;11(2):157-62.
The normal squamous epithelium of the uterine cervix was investigated in 50 foetuses and newborns, as well as in 207 adult women operated upon because of various benign conditions of the uterus. The epithelium was divided according to the presence or the absence of prominent epithelial papillae. Epithelial papillae occurred in 32% of the cervices in the paediatric age and in 17% in adult women. They were present in the whole squamous epithelium covering the portio vaginalis in all pediatric patients. In 49% of the adult patients epithelial papillae covered the whole portio and/or the transitional zone; in the remaining 51% only a reduced area presented epithelial papillae. Micrometric determinations demonstrated that normal epithelium with papillar formation was thicker than epithelium with smooth epithelial border. This was most prominent in the paediatric patients. The possibility that oestrogenic stimulation (in paediatric patients) and oestrogenic stimulation as well as chronic stromal inflammation (in adult patients) could account for the formation of prominent epithelial papillae was discussed.
对50例胎儿和新生儿以及207例因各种子宫良性疾病接受手术的成年女性的子宫颈正常鳞状上皮进行了研究。根据是否存在明显的上皮乳头对上皮进行分类。小儿年龄组中32%的宫颈出现上皮乳头，成年女性中为17%。所有儿科患者覆盖阴道部的整个鳞状上皮中均有上皮乳头。49%的成年患者上皮乳头覆盖整个阴道部和/或移行带；其余51%仅局部区域有上皮乳头。显微镜测量表明，有乳头形成的正常上皮比上皮边界光滑的上皮更厚。这在儿科患者中最为明显。讨论了（儿科患者中的）雌激素刺激以及（成年患者中的）雌激素刺激和慢性基质炎症导致明显上皮乳头形成的可能性。
