Lombard-Bohas C, Mornex F, Saurin J C
Unité d'oncologie médicale, CHU Edouard-Herriot, Lyon, France.
Cancer Radiother. 1997;1(5):547-54. doi: 10.1016/s1278-3218(97)89637-0.
Pancreatic cancer still have bad prognosis. At the time of diagnosis, less than 10% of patients can undergo surgery with an overall 5-year survival rate of less than 2%. For patients with localized pancreatic adenocarcinoma, the combination of radiation therapy and chemotherapy has been shown to control symptoms and to enhance patient survival. This treatment should be proposed to all the patients with good performance status and without icterus. Pain management should be optimized and often need morphinic and co-antalgic (anticonvulsivants, steroids) consumption. The celiac plexus block with alcohol gives an excellent pain relief and should be more frequently used.
胰腺癌的预后仍然很差。在确诊时，不到10%的患者能够接受手术，总体5年生存率低于2%。对于局限性胰腺腺癌患者，放疗和化疗联合已被证明可控制症状并提高患者生存率。这种治疗方案应推荐给所有身体状况良好且无黄疸的患者。疼痛管理应得到优化，通常需要使用吗啡类药物和辅助镇痛药（抗惊厥药、类固醇）。酒精性腹腔神经丛阻滞能有效缓解疼痛，应更频繁地使用。
