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胸主动脉粥样硬化性动脉瘤

[Atheromatous aneurysms of the thoracic aorta].

作者信息

Villard J

机构信息

Unité de chirurgie cardiaque et vasculaire, hôpital cardiovasculaire Louis-Pradel, Lyon.

出版信息

Arch Mal Coeur Vaiss. 1997 Dec;90(12 Suppl):1741-9.

PMID:9587460
Abstract

Atheromatous aneurysms of the thoracic aorta are much less common than those of the abdominal aorta. Associated atherosclerosis of the coronary, cerebral and peripheral limb arteries is observed in 16, 10 and 11% of cases, respectively. Ultrasonography. CT scanning, and mostly MRI and digitised angiography provide very accurate morphological data. The natural history is dominated by the risk of rupture with a 3 year survival of 50% in aneurysms with a diameter superior to 5 cm. The surgical indication should be considered in cases of aneurysms with diameters over 5 cm after full carotid, coronary, respiratory and renal investigations. Surgery is simple in descending aortic aneurysms but more complicated in aneurysms of the transverse and descending aorta, especially in long lesions. Technical innovations have reduced the incidence of both cerebral complications after surgery of the aortic arch by improved cerebral protection and of medullary complications after surgery of the descending thoracic aorta, especially of thoraco-abdominal aneurysms, by better medullary protection against ischaemia during aortic clamping. The operative results have a mortality of: 3% for aneurysms of the ascending aorta: 10% for aneurysms of the aortic arch: 9% with a 15% risk of paraplegia, for long aneurysms of the descending thoracic aorta.

摘要

胸主动脉粥样硬化性动脉瘤比腹主动脉粥样硬化性动脉瘤少见得多。分别有16%、10%和11%的病例伴有冠状动脉、脑动脉和外周肢体动脉粥样硬化。超声检查、CT扫描,以及主要是MRI和数字化血管造影可提供非常准确的形态学数据。其自然病史主要是破裂风险,直径超过5cm的动脉瘤3年生存率为50%。在对颈动脉、冠状动脉、呼吸系统和肾脏进行全面检查后,直径超过5cm的动脉瘤应考虑手术指征。降主动脉瘤手术简单,但横主动脉和降主动脉瘤手术更复杂,尤其是长病变。技术创新通过改善脑保护降低了主动脉弓手术后脑并发症的发生率,通过在主动脉钳夹期间更好地保护脊髓免受缺血,降低了降胸主动脉手术后脊髓并发症的发生率,尤其是胸腹主动脉瘤。手术结果的死亡率为:升主动脉瘤为3%;主动脉弓瘤为10%;降胸主动脉长动脉瘤为9%,有15%的截瘫风险。

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