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[胎盘所谓窒息性浸润的发生及意义。I. 组织学结果]

[Genesis and significance of so-called asphyxial infiltrates in the placenta. I. Histologic results].

作者信息

Emmrich P, Dalitz H, Rother P

机构信息

Institut für Pathologie, Universität Leipzig, Deutschland.

出版信息

Ann Anat. 1998 Apr;180(2):123-30.

PMID:9587635
Abstract

The conventional conception of the cause and formal pathogenesis of so-called "asphyxial infiltrates" of the placenta is presented. Morphological examples are given. Our study included 561 newborn cases. Eighty two cases (14.6%) had such cell infiltrates, and there were 6 cases with phlegmoneous inflammation of the fetal membranes. These morphological findings correlated with the following clinical characteristics: term of birth, weight classes of newborns, Clifford-signs, clinical risks with respect to hypertension, the course of pregnancy and particularly the risk of inflammation. Additional correlates were the clinical statement of hypoxia and acidosis in newborns. We discovered relationships between these cell infiltrates and the Clifford-signs, and to some clinical risks (especially those for inflammation), but not to hypoxia and acidosis of the newborn. Our results show, that there are no relations between the conventional "Asphyxial infiltrates" of the placenta and the hypoxia and acidosis observed in newborns.

摘要

本文介绍了胎盘所谓“窒息性浸润”的病因及正式发病机制的传统概念,并给出了形态学示例。我们的研究纳入了561例新生儿病例。其中82例(14.6%)存在此类细胞浸润,6例胎膜有蜂窝织炎。这些形态学发现与以下临床特征相关:出生孕周、新生儿体重等级、克利福德征、高血压相关临床风险、妊娠过程,尤其是炎症风险。其他相关因素包括新生儿缺氧和酸中毒的临床表现。我们发现这些细胞浸润与克利福德征以及一些临床风险(尤其是炎症风险)之间存在关联,但与新生儿缺氧和酸中毒无关。我们的结果表明,胎盘传统的“窒息性浸润”与新生儿观察到的缺氧和酸中毒之间不存在关联。

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