Riezzo G, Chiloiro M, Pezzolla F, Lorusso D
Laboratory of Experimental Pathophysiology, Scientific Institute of Gastroenterology, Castellana Grotte, Bari, Italy.
Arch Physiol Biochem. 1997 Oct;105(6):545-51. doi: 10.1076/apab.105.6.545.3275.
To investigate the effects of cholecystectomy on gastric motor function, 13 patients with symptomatic gallstones were studied before and 8-12 months after surgery. Twelve healthy subjects entered the study as control group. The cutaneous electrogastrography and ultrasound examination of gastric emptying were simultaneously performed at pre- and post-prandial states. The dominant gastric frequency and its coefficient of variation were not affected by surgery. After cholecystectomy, an increase in normal 3 cpm wave percentage and a decrease in power ratio were found (P < 0.05 and P < 0.01, respectively). Gastric emptying recorded after cholecystectomy was faster than before surgery (306.9 +/- 15.9 min vs 336.9 +/- 11.8 min, respectively; P < 0.05). Such changes were associated with the relief of symptoms, and the comparison between patients and controls showed a normalization of the gastric electrical activity and gastric emptying after surgery. In conclusion, in symptomatic patients, gallstones are associated with motor dysfunctions, and cholecystectomy seems to induce a normalization of gastrointestinal motility.
为研究胆囊切除术对胃运动功能的影响，对13例有症状胆结石患者在手术前及术后8 - 12个月进行了研究。12名健康受试者作为对照组进入研究。在餐前和餐后状态同时进行胃电图皮肤检测和胃排空超声检查。胃的主导频率及其变异系数不受手术影响。胆囊切除术后，正常3次/分钟波百分比增加，功率比降低（分别为P < 0.05和P < 0.01）。胆囊切除术后记录的胃排空比手术前更快（分别为306.9 +/- 15.9分钟和336.9 +/- 11.8分钟；P < 0.05）。这些变化与症状缓解相关，患者与对照组的比较显示术后胃电活动和胃排空恢复正常。总之，在有症状的患者中，胆结石与运动功能障碍有关，胆囊切除术似乎可使胃肠动力恢复正常。
