Suzuki A, Tsutsumi H, Kusakabe K, Kuwahara M, Sugano S, Tanigawa M
SLA Research, Inc., Nagano, Japan.
Lab Anim. 1998 Apr;32(2):165-72. doi: 10.1258/002367798780599938.
A Holter recording system was established for the Göttingen miniature swine. For this purpose, we first developed a jacket to hold a Holter recording set, and subsequently determined a bipolar lead suitable for obtaining stable electrocardiogram (ECG) recording without artifacts. To make the jacket, we measured the lengths of eight sites of the body of 14 miniature swine. Several types of jackets were made and tested. We observed the behaviour of animals with these jackets by videotape recorder (VTR) recording. These observations permitted development of a jacket suitable for Holter recording. The jacket permits easy placement of the recorder, and long-term ECG recording can be performed without difficulty. In order to determine a suitable lead for long-term recording, we recorded ECGs from six adult miniature swine using three types of leads, the M-X, R-L and A-B leads. The R-L lead frequently exhibited baseline drift, and QRS complexes often disappeared in this lead due to low amplitude. ECG recording with the M-X and A-B leads was of sufficient quality to permit analysis. This system is expected to be useful for further cardiovascular research in miniature swine.
为哥廷根小型猪建立了一个动态心电图记录系统。为此，我们首先制作了一个用于固定动态心电图记录装置的外套，随后确定了一种适合获得无伪迹的稳定心电图（ECG）记录的双极导联。为了制作外套，我们测量了14只小型猪身体八个部位的长度。制作并测试了几种类型的外套。我们通过录像机（VTR）记录观察了穿着这些外套的动物的行为。这些观察结果使得开发出一种适合动态心电图记录的外套成为可能。该外套便于放置记录仪，并且可以轻松地进行长期心电图记录。为了确定适合长期记录的导联，我们使用三种导联，即M-X、R-L和A-B导联，对六只成年小型猪进行了心电图记录。R-L导联经常出现基线漂移，并且由于振幅较低，该导联的QRS波群常常消失。使用M-X和A-B导联进行的心电图记录质量足以进行分析。该系统有望对小型猪的进一步心血管研究有用。
