Alton K, Kofler J
Institut für Pathologie und Gerichtliche Veterinärmedizin, Veterinärmedizinischen Universität Wien.
Tierarztl Prax Ausg G Grosstiere Nutztiere. 1998 Apr;26(2):73-7.
Clinical, radiographic, gross-pathological and histological findings in a squamous cell carcinoma of the claw matrix in a three-year-old Simmental cow are described. The cow showed severe lameness of the right foreleg. Radiological examination revealed a large osteolytic focus in the medial distal phalanx. The tentative clinical diagnosis of apical pedal bone necrosis was followed by amputation and pathological examination of the claw. The horn capsule showed no lesions. Pathological examination revealed soft consistency of pedal bone and the cut surface showed a yellowish crumbling material, which had replaced most of the pedal bone. Histologically, infiltration and osteolysis of distal pedal bone by a squamous cell carcinoma was ascertained. This claw tumor has not been reported until now. Clinically, it resembles apical pedal bone necrosis and therefore should be included in the differential diagnosis.
描述了一头3岁西门塔尔母牛爪甲床鳞状细胞癌的临床、影像学、大体病理和组织学检查结果。该母牛右前肢严重跛行。放射学检查显示远端内侧指骨有一个大的溶骨性病灶。初步临床诊断为蹄尖骨坏死,随后对患爪进行截肢和病理检查。角鞘未发现病变。病理检查显示蹄骨质地变软,切面可见淡黄色易碎物质,已取代了大部分蹄骨。组织学检查确定为鳞状细胞癌浸润并溶解远端蹄骨。这种爪部肿瘤此前未见报道。临床上,它类似于蹄尖骨坏死,因此应列入鉴别诊断。