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与利培酮治疗相关的强迫症状。

Obsessional symptoms associated with risperidone treatment.

作者信息

Mahendran R

机构信息

Woodbridge Hospital and Institute of Mental Health, Buangkok Green, Singapore.

出版信息

Aust N Z J Psychiatry. 1998 Apr;32(2):299-301. doi: 10.3109/00048679809062744.

DOI:10.3109/00048679809062744
PMID:9588312
Abstract

OBJECTIVE

The aim of this paper is to report the occurrence of obsessional symptoms with risperidone treatment in a patient with no past history of obsessive-compulsive symptoms.

CLINICAL PICTURE

A 26-year-old, single, Chinese lady with a chronic untreated schizophrenic illness was prescribed risperidone after she experienced side effects with other antipsychotic medication. After the second week on risperidone, she developed obsessional symptoms.

TREATMENT AND OUTCOME

The obsessional symptoms responded to treatment with low dose clomipramine.

CONCLUSION

The potential for the newer antipsychotic medication to precipitate or exacerbate obsessive-compulsive symptoms during treatment for schizophrenia must be borne in mind.

摘要

目的

本文旨在报告一名既往无强迫症状病史的患者在使用利培酮治疗期间出现强迫症状的情况。

临床表现

一名26岁的单身中国女性,患有未经治疗的慢性精神分裂症,在使用其他抗精神病药物出现副作用后,开始服用利培酮。服用利培酮第二周后,她出现了强迫症状。

治疗及结果

强迫症状经低剂量氯米帕明治疗后有反应。

结论

在精神分裂症治疗期间,必须牢记新型抗精神病药物有引发或加重强迫症状的可能性。

相似文献

1
Obsessional symptoms associated with risperidone treatment.与利培酮治疗相关的强迫症状。
Aust N Z J Psychiatry. 1998 Apr;32(2):299-301. doi: 10.3109/00048679809062744.
2
Obsessive-compulsive symptoms in schizophrenia: their relationship with clinical features and pharmacological treatment.精神分裂症中的强迫症状:它们与临床特征及药物治疗的关系。
J Psychiatr Pract. 2010 Jul;16(4):235-42. doi: 10.1097/01.pra.0000386909.84289.ee.
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Differential response of psychotic and obsessive symptoms to risperidone in an adolescent.一名青少年的精神病性症状和强迫症状对利培酮的不同反应。
J Child Adolesc Psychopharmacol. 1996 Summer;6(2):139-45. doi: 10.1089/cap.1996.6.139.
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Obsessive-compulsive symptoms associated with clozapine and risperidone treatment: three case reports and review of the literature.与氯氮平和利培酮治疗相关的强迫症状:三例病例报告及文献综述
Kaohsiung J Med Sci. 2004 Jun;20(6):295-301. doi: 10.1016/S1607-551X(09)70121-4.
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Obsessive-compulsive symptoms in patients with schizophrenia: a naturalistic cross-sectional study comparing treatment with clozapine, olanzapine, risperidone, and no antipsychotics in 543 patients.精神分裂症患者的强迫症状:一项自然横断面研究,比较了 543 例患者使用氯氮平、奥氮平、利培酮和无抗精神病药物治疗的效果。
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Symptoms in neuroleptic-naive, first-episode schizophrenia: response to risperidone.初发未使用过抗精神病药物的精神分裂症患者的症状:对利培酮的反应
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Clomipramine treatment of obsessive compulsive symptomatology in schizophrenic patients.氯米帕明治疗精神分裂症患者的强迫症状
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J Clin Psychopharmacol. 2000 Aug;20(4):410-6. doi: 10.1097/00004714-200008000-00004.

引用本文的文献

1
Second generation antipsychotic-induced obsessive-compulsive symptoms in schizophrenia: a review of the experimental literature.第二代抗精神病药物诱发精神分裂症的强迫症状:实验文献综述
Curr Psychiatry Rep. 2014 Nov;16(11):510. doi: 10.1007/s11920-014-0510-8.
2
Obsessive-compulsive disorder in schizophrenia: clinical characteristics and treatment.精神分裂症中的强迫症:临床特征与治疗
CNS Drugs. 2004;18(14):989-1010. doi: 10.2165/00023210-200418140-00004.