佩吉特病骨扫描时肾脏显影的意义
Significance of renal visualization during bone scanning in Paget's disease.
作者信息
Winter P F, Johnson P M
出版信息
Nuklearmedizin. 1976 Jun;15(3):131-4.
PMID:958899
Abstract
In 17 of 26 patients with extensive, symptomatic Paget's disease poor renal visualization was noted on bone scanning with 99mTc-diphosphonate. Renal function was normal in all patients. The intensity of the renal image proved to be inversely related to the extent and metabolic activity of the Pagetic process. This finding supports the hypothesis that in Paget's disease the balance between skeletal and renal extraction of circulating tracer amy be displaced in favor of the former.
摘要
在26例患有广泛性、症状性佩吉特病的患者中，17例在使用99mTc - 二膦酸盐进行骨扫描时发现肾脏显影不佳。所有患者的肾功能均正常。肾脏图像的强度被证明与佩吉特病病变的范围和代谢活性呈负相关。这一发现支持了这样一种假说，即在佩吉特病中，循环示踪剂在骨骼和肾脏摄取之间的平衡可能会偏向于前者。
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