Hunt L W
Mayo Clinic and Graduate School of Medicine, Rochester, Minnesota, USA.
Drug Saf. 1998 May;18(5):357-68. doi: 10.2165/00002018-199818050-00005.
The treatment for asthma usually involves a combination of drugs used for bronchodilation and to treat underlying airway inflammation. When asthma is severe, the regimen used to treat asthma can become quite complicated, often using as many as 3 or 4 separate pharmacological agents. As patients with asthma get older, their medication regimen can become even more complex with the development of numerous other age-related diseases requiring their own list of medications. Diseases of the joints, diseases of the eye, cardiovascular disease, neurological disease and urological problems represent the most common conditions that patients develop, at times needing medications which might interfere with asthma management. Many of these diseases require the use of nonsteroidal anti-inflammatory agents, well known to provoke wheezing in patients with intrinsic asthma, and diseases of the eye and cardiovascular system frequently require use of beta-blockers which can cause or exacerbate asthma. Managing patients with asthma who have other diseases requires constant supervision of their medication usage and careful and cautious review of the entire list of medications at each presentation.
哮喘的治疗通常涉及用于支气管扩张和治疗潜在气道炎症的药物组合。当哮喘严重时，用于治疗哮喘的方案可能会变得相当复杂，常常使用多达3或4种不同的药物制剂。随着哮喘患者年龄的增长，由于出现了许多其他需要各自用药清单的与年龄相关的疾病，他们的用药方案可能会变得更加复杂。关节疾病、眼部疾病、心血管疾病、神经系统疾病和泌尿系统问题是患者最常出现的病症，有时需要使用可能干扰哮喘治疗的药物。其中许多疾病需要使用非甾体抗炎药，众所周知，这些药物会诱发内源性哮喘患者喘息，而眼部和心血管系统疾病常常需要使用可能导致或加重哮喘的β受体阻滞剂。治疗患有其他疾病的哮喘患者需要持续监督他们的用药情况，并在每次就诊时仔细谨慎地审查整个用药清单。
